BACKGROUND: Previous research suggests that exposures to air pollution and nonoptimal temperatures are associated with a ...

BACKGROUND: Despite the significant global impact of the COVID-19 pandemic, limited studies have investigated the long-term ...

BACKGROUND: Recent studies have highlighted the deleterious role of high phosphate intake in hypertension by means of ...

The win ratio is a method for analyzing a hierarchical composite outcome. It has been most widely used in randomized clinical trials (RCTs) in cardiovascular disease. We performed a review of ...

The METTL3 and METTL14 amino acid sequences are highly conserved between mouse and human. To further investigate the role of METTL3/METTL14 methyltransferase in sarcomere maturation in human ...

View all available purchase options and get full access to this article. Lindman BR, Clavel MA, Mathieu P, Iung B, Lancellotti P, Otto CM, Pibarot P. Calcific aortic stenosis. Nat Rev Dis Primers.

The “open vein hypothesis” postulates that early thrombus clearance and restoration of venous blood flow may prevent postthrombotic syndrome after proximal deep vein thrombosis. Since its proposal ...

Venoarterial extracorporeal membrane oxygenation (ECMO) provides full hemodynamic support for patients with cardiogenic shock, but optimal timing of ECMO initiation remains uncertain. We sought to ...

Cardiac metabolic dysfunction is a hallmark of heart failure (HF). Estrogen-related receptors ERRα and ERRγ are essential regulators of cardiac metabolism. Therefore, activation of ERR could be a ...

There are a lack of randomized controlled trial data comparing outcomes of different catheter-based interventions for intermediate-risk pulmonary embolism. PEERLESS is a prospective, multicenter, ...

The EF-hand Ca 2+ sensor protein S100A1 has been identified as a molecular regulator and enhancer of cardiac performance. The ability of S100A1 to recognize and modulate the activity of targets such ...

The effects of treatments for heart failure (HF) may vary among patients according to left ventricular ejection fraction (LVEF). In FINEARTS-HF (Finerenone Trial to Investigate Efficacy and Safety ...